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Index > Protein center > HAGH(Gene name) > Human
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  • HAGH (Gene name),
  • Hydroxyacylglutathione hydrolase, mitochondrial (Protein name ),  GLO2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    HAGH(GLO2;HAGH1);
    Protein name:
    Hydroxyacylglutathione hydrolase, mitochondrial;
    Alternative:
    Glyoxalase II(Glx II);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
    Subcellular Location:
    Isoform 2 Cytoplasm
    Protein Attributes:
    Sequence length:
    308
    Sequence:
    50:
    MVVGRGLLGR | RSLAALGAAC | ARRGLGPALL | GVFCHTDLRK | NLTVDEGTMK | 
    100:
    VEVLPALTDN | YMYLVIDDET | KEAAIVDPVQ | PQKVVDAARK | HGVKLTTVLT | 
    150:
    THHHWDHAGG | NEKLVKLESG | LKVYGGDDRI | GALTHKITHL | STLQVGSLNV | 
    200:
    KCLATPCHTS | GHICYFVSKP | GGSEPPAVFT | GDTLFVAGCG | KFYEGTADEM | 
    250:
    CKALLEVLGR | LPPDTRVYCG | HEYTINNLKF | ARHVEPGNAA | IREKLAWAKE | 
    300:
    KYSIGEPTVP | STLAEEFTYN | PFMRVREKTV | QQHAGETDPV | TTMRAVRREK | 
    308:
    DQFKMPRD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    UniGene:
    String:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    E12649h
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    Packing:
    96T
    ELISA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
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    Packing:
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    ELISA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
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    Packing:
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    ELISA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    E12649c
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    Packing:
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    ELISA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    E12649r
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    Packing:
    96T
    CLIA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    U12649h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    U12649b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    U12649r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    U12649c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    U12649m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Polyclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    P12649Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Polyclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    P12649Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Cat.:
    P12649Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Monoclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Monoclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Monoclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Monoclonal Antibody for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Protein for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Protein for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Protein for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Protein for Human Hydroxyacylglutathione hydrolase, mitochondrial
    Protein for Human Hydroxyacylglutathione hydrolase, mitochondrial

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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
      tissue: Thalamus.
    2. 2.
      "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."
      Daniels R.J. , Peden J.F. , Lloyd C. , Horsley S.W. , Clark K. , Tufarelli C. , Kearney L. , Buckle V.J. , Doggett N.A. , Flint J. , Higgs D.R.
      Hum. Mol. Genet.10:339-352(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Cervix.
      tissue: Uterus.
    5. 5.
      "Molecular cloning, heterologous expression, and characterization of human glyoxalase II."
      Ridderstroem M. , Saccucci F. , Hellman U. , Bergman T. , Principato G. , Mannervik B.
      J. Biol. Chem.271:319-323(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 37-308 (ISOFORMS 1/2)
      tissue: Liver.
    6. 6.
      "The human hydroxyacylglutathione hydrolase (HAGH) gene encodes both cytosolic and mitochondrial forms of glyoxalase II."
      Cordell P.A. , Futers T.S. , Grant P.J. , Pease R.J.
      J. Biol. Chem.279:28653-28661(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;ALTERNATIVE INITIATION;ALTERNATIVE SPLICING (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
    7. 7.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-229;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue."
      Cameron A.D. , Ridderstroem M. , Olin B. , Mannervik B.
      Structure7:1067-1077(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 49-308 IN COMPLEX WITH SUBSTRATE ANALOGS AND ZINC IONS
      tissue: Liver.
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